Naphthoquinones may cause oxidative stress in exposed cells and, therefore, affect redox signaling.Here, contributions of redox cycling and alkylating properties of quinones (both natural and synthetic, such as plumbagin, juglone, lawsone, menadione, methoxy-naphthoquinones, and others) thorogood 804-3236 to cellular and inter-cellular signaling pr
HDAC1 deregulation promotes neuronal loss and deficit of motor function in stroke pathogenesis
Abstract Stroke is a common cause of death worldwide and leads to disability and cognitive dysfunction.Ischemic stroke and hemorrhagic stroke are major categories of stroke, accounting for 68% and 32% of strokes, respectively.Each year, 15 million people experience stroke worldwide, and the stroke incidence is rising.Epigenetic modifications regula
A Construction for Providing Reusability to Mobile Phone-Based e-Tickets
Nowadays, the use of electronic tickets in public transport is a reality.Several mobile phone-based nobivac 1-dappv for puppies e-ticket systems have been proposed so far.Even so, very few of them include reusability in the sense that a single e-ticket allows to make several journeys.Although the identity of users is usually hidden behind a pseudon
A Numerical Study of a Soil-Nail-Supported Excavation Pit Subjected to a Vertically Loaded Strip Footing at the Crest
Soil nailing is a prevalent and cost-effective technique employed to reinforce and enhance the stability of precarious natural or cut slopes; however, its application as a primary support system to prevent collapses or cave-ins during foundation excavation could be more frequent.To better understand the behavior of such a support system, this study